Lidocaine Patch For Back Pain-Two open studies show that lidocaine patches (Lidoderm®, Endo Pharmaceuticals) may be useful in the treatment of osteoarthritis of the knee (OA) and chronic low back pain. 1, 2? Both studies were sponsored by the manufacturer and have resulted in additional trials with the product in both new indications, this time with placebo control.
The patches (containing 5% lidocaine) are currently approved in the USA. UU Only to relieve the pain associated with postherpetic neuralgia (PHN).
The results of an open study were presented here last week at a joint meeting of the American Pain Society and the Canadian Pain Society.
The principal investigator of the osteoarthritis study, Dr. Chris Codding (Center for Health Research, Oklahoma City, OK), said the data suggest that the lidocaine patch “may reduce the quality of pain commonly associated with osteoarthritis” and It could be a useful treatment for these patients. population
The coding told the rheumatism cable that he started using non-approved label products in some of his patients with osteoarthritis, especially those who can not tolerate oral therapy, such as nonsteroidal anti-inflammatory drugs (NSAIDs).
One of the researchers involved in the study of low back pain, Dr. Joseph Gimbel (Arizona Research Center, Phoenix), described the lidocaine patch as “an innovative treatment for postherpetic neuralgia” and said he was “encouraged” for a new investigation. “We are constantly looking for new and innovative ways to help patients reduce chronic pain,” he added.
OA research involves 100 patients with moderate to severe osteoarthritis who have used multiple medications. Patients who take the drug on a regular basis (for example, NSAIDs every day) to go on a regimen of regular and use the patch as adjuvant therapy (n = 88), but who were taking the drug in one were asked “very necessary “to refrain from using the lidocaine patch as monotherapy (n = 12).
Participants are issued every two hours every two hours; They can pick up some patches to cover all the painful areas, but they should be consistent with the number of patches they use every day.
The study lasted 2 weeks, and efficacy was assessed using questionnaires from patients using the neuropathic pain scale (NPS). This assessment tool measures 10 different pain components (including acute, deep, dull and superficial pain, general intensity and general discomfort).